Adverse events should be reported. Healthcare professionals are asked to report any suspect adverse events via their national reporting system. Adverse events should also be reported to HRA Pharma at firstname.lastname@example.org.
ellaOne® significantly reduces the risk of unintended pregnancy vs levonorgestrel.1
A meta-analysis of the two, large, head-to-head trials comparing ellaOne® with levonorgestrel showed that the risk of pregnancy was significantly reduced with ulipristal acetate compared to levonorgestrel :1
For a woman who comes to you for help, what does this mean ?
Her risk of getting pregnant is :
of unprotected intercourse
With no intervention
5.5 % 5.5 %
2.3 % 2.2 %
0.9 % 1.4 %
P- value: 0.035
P- value: 0.046
Two comparative non-inferiority studies showed ellaOne® is at least as effective in preventing pregnancy as levonorgestrel.1,2
Ovulation is a result of a surge in luteinising hormone (LH). ellaOne® delays ovulation by inhibiting or delaying the LH surge.1
If the woman is due to ovulate tomorrow or the next day after unprotected sex, when the risk of pregnancy is highest, only ellaOne® can delay ovulation1
This is when LH has started to surge but has not yet peaked. At this time, levonorgestrel will not prevent the follicle from rupturing whereas ellaOne® is highly effective1
Intake after LH surge, but before peak1
If she is due to ovulate 3 or more days after unprotected intercourse, both ellaOne® and levonorgestrel can delay ovulation. 1 However, ellaOne® remains more effective in preventing follicle rupture and therefore unintended pregnancy.1
Intake before LH surge1
If the woman has already ovulated, or is due to ovulate, in the immediate 24 hours following unprotected intercourse, no emergency contraceptive pill will help1
This is because the LH has already peaked, meaning the ovulation process is at a point where it cannot be stopped, or has already happened.
This explains why:
• Speed of emergency contraceptive pill intake is critical
• Emergency contraception is not 100% effective
Intake after LH peak1
ellaOne® can delay ovulation even when it is about to happen (when risk of fertilisation is highest)1
ellaOne® – specifically developed for emergency contraception1
ellaOne® is an emergency contraception pill which contains 30 mg ulipristal acetate2, and which was specifically developed for EC1
Ulipristal acetate is an orally-active selective progesterone receptor modulator (SPRM)2
Having undergone a rigorous, centralised European Union (EU) authorisation process, it first became available as a prescription medicine in the EU in 20091
Since then it has been made available in over 70 countries as a prescription medicine1 and now for pharmacy supply, without prescription across the EU
ellaOne® works by inhibiting or delaying ovulation2
What is ellaOne®?
ellaOne® is an emergency contraceptive pill intended to prevent pregnancy after unprotected sexual intercourse or contraceptive failure2
ellaOne® should be taken as soon as possible, but no later than 120 hours (5 days) after UPSI or contraceptive failure2
ellaOne® is for women of reproductive age who want to avoid unintended pregnancy2
How to use ellaOne® ?
The treatment consists of one tablet to be taken orally as soon as possible after UPSI or contraceptive failure2
ellaOne® does not offer protection from pregnancy for subsequent acts of unprotected sex. Women should be advised to use a reliable barrier method until their next menstrual period2
Although the use of ellaOne® does not contraindicate the continued use of regular hormonal contraception, ellaOne® may reduce its contraceptive action2. Therefore, if a woman wishes to start or continue using hormonal contraception, she can do so after using ellaOne®, however, she should be advised to use a reliable barrier method until the next menstrual period2.
The tablet can be taken with or without food2
If vomiting occurs within 3 hours of ellaOne® intake, another tablet should be taken2
ellaOne® can be taken at any time during the menstrual cycle2
What ellaOne® is not
ellaOne® is not a regular contraceptive, it is for occasional use only2
In any case, women should be advised to adopt a regular method of contraception.
ellaOne® does not cause abortion, it does not interrupt an existing pregnancy2
ellaOne® does not protect from sexually transmitted infections5